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CHEM-20

Alternative Names 
SMAC20, sequential multichannel analysis with computer-20, SMA20

Definition
CHEM-20 is a set of 20 tests that are performed on a sample of blood. The results give an overview of blood chemistry that is very useful to the healthcare provider.

CHEM-20 indicates the concentrations or levels in the blood of key electrolytes or minerals, enzymes, sugars, proteins and metabolites, or substances produced by chemical processes. Blood delivers nutrients to all of the body's cells and tissues. Blood carries waste products from these cells and tissues, as well. An analysis of blood chemistry can reveal a lot about problems in specific cells and tissues.

Who is a candidate for the test? 
This test is normally done to evaluate how a number of products, such as proteins, sugars and enzymes, are being used in the body. This test can help a healthcare provider diagnose diseases.

How is the test performed? 
To perform this set of tests, a blood sample is taken from a vein on the forearm or hand. First, the skin over the vein is cleaned with an antiseptic. Next, a strong rubber tube, or tourniquet, is wrapped around the upper arm. This enlarges the veins in the lower arm by restricting blood flow through them. A thin needle is gently inserted into a vein, and the tourniquet is removed. Blood flows from the vein through the needle, and is collected in a syringe or vial for testing in the laboratory. After the needle is withdrawn, the puncture site is covered for a short time to prevent bleeding.

What is involved in preparation for the test? 
A person should request specific instructions about preparation for the CHEM-20 from his or her healthcare provider.

What do the test results mean? 
The normal values for substances measured by CHEM-20 are as follows:
  • Albumin = 3.9 to 5.0 mg/dl
  • Alkaline phosphatase = 44 to 147 IU/liter
  • Alanine transaminase (ALT or SGPT) = 6 to 59 IU/liter
  • Aspartate aminotransferase (AST or SGOT) = 10 to 34 IU/liter
  • Blood urea nitrogen (BUN) = 7 to 20 mg/dl
  • Serum calcium = 8.5 to 10.9 mg/dl
  • Serum chloride = 101 to 222 mmol/liter
  • Carbon dioxide (CO2) = 20 to 29 mmol/liter
  • Creatinine = 0.8 to 1.4 mg/dl
  • Direct bilirubin = 0 to 0.3 mg/dl
  • Gamma-glutamyl transpeptidase (GGT) = 0 to 51 IU/liter
  • Glucose = 64 to 128 mg/dl
  • Lactate dehydrogenase (LDH) = 105 to 333 IU/liter
  • Serum phosphorus = 2.4 to 4.1 mg/dl
  • Potassium test = 3.7 to 5.2 mEq/liter
  • Total bilirubin = 0.2 to 1.9 mg/dl
  • Total cholesterol = 100 to 240 mg/dl
  • Total protein = 6.3 to 7.9 g/dl
  • Uric acid = 4.1 to 8.8 mg/dl
Abbreviations:
  • dl = deciliter
  • mg = milligram
  • mmol = millimole
  • mEq = milliequivalent
  • g = gram
  • IU = International Unit
Author: David T. Moran, MD
Reviewer: Eileen McLaughlin, RN, BSN
Last Updated: 05/16/00
Contributors
Potential conflict of interest information for reviewers available on request
 


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