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obstructive uropathy

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Kidneys and adrenal glands

Alternative Names
post-renal nephropathy

Definition
Obstructive uropathy is a blockage of the normal flow of urine somewhere along the urinary tract.

What is going on in the body?
The urinary tract consists of the kidney, the bladder, the ureters, and the urethra. Obstruction can occur anywhere along this tract. Obstruction of urine flow increases the pressure to the kidney and can result in acute renal failure.

What are the signs and symptoms of the condition?
Symptoms of obstructive uropathy include: What are the causes and risks of the condition?
Obstructive uropathy may be caused by: How is the condition diagnosed?
The history, a physical examination, and laboratory tests help in diagnosing the condition. X-rays may be taken to look for kidney stones.

Ultrasound may show swelling of the kidneys and enlargement of the renal collection system, called hydronephrosis. Or if the obstruction is lower, it may show enlargement of the ureters, called hydroureter.

If the ultrasound does not show an obstruction, an intravenous pyelogram may be done. This test shows how the urine flows throughout the urinary tract. A contrast agent is injected into a blood vessel and is quickly excreted into the urine. Multiple x-rays are taken to show the flow of urine from the kidneys to the bladder. An obstruction shows up as a blockage of this flow. Retrograde pyelograms are similar. They show the flow of urine from the kidney to the urethra.

What are the treatments for the condition?
Treatment focuses on relieving the obstruction with surgery, bypass, or medications.

If the cause is benign prostatic hyperplasia, that condition is treated. BPH can be treated with medications, intermittent or continuous use of a urinary catheter in the bladder, or prostate surgery.

If the obstruction is at a higher level, two kinds of tubes can be used to bypass it. A catheter can be placed in the bladder, or a tube is placed through the skin close to the obstructed ureter. Other surgical procedures include redirecting the ureters or placing stents in them.

What are the side effects of the treatments?
Any urinary catheterisation increases the risk of urinary tract infections. Surgery complications include risk of infection, bleeding, or reaction to the anaesthesia, such as stomach upset or allergic reaction.

What happens after treatment for the condition?
Recovery of kidney function often depends on how long the obstruction lasts. If it is less than 7 days, recovery is usually complete. If it's less than 2 weeks, the chance of renal recovery is about 70%. Obstruction that lasts up to 30 days has only a 30% chance of renal recovery. After 2 to 3 months of obstruction, renal recovery is unlikely. Some people continue to have kidney problems for a long period of time after obstruction.

How is the condition monitored?
Any new or worsening symptoms should be reported to the doctor. The person will have periodic visits with the doctor to monitor kidney function.

Author: Crystal R. Martin, MD
Reviewer: HealthAnswers Australia Medical Review Panel
Editor: Dr David Taylor, Chief Medical Officer HealthAnswers Australia
Last Updated: 1/10/2001
Contributors
Potential conflict of interest information for reviewers available on request


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